Virology

The Section for Virology conducts research both in endemic viral diseases e.g. swine influenza and in exotic viral diseases e.g. swine fever, Foot-and-mouth disease virus (FMD), and Viral haemorrhagic septicemia (VHS) in livestock such as pigs, cattle, and fish.

Our research is centered on the diseased animal, and the work tries to clarify the following:
  • What virus causes the disease and how the animal was infected?
  • How the virus and the infected animals interact and how the disease emerges?
  • How the virus spread to other animals and in some cases to humans?
  • How to prevent the spread of viruses, and thereby prevent additional cases of the disease?
Examples of our research into disease mechanisms include studies of how swine influenza infects pigs and humans differently depending on the distribution of sialic acid receptors on the surface of lung epithelial cells. Also, we conduct studies of how the different parts of the swine fever virus genome contribute to causing damage and disease after infection.

We use both classic virus culturing methods and infection experiments in our classified laboratories and animal facilities as well as new molecular biology techniques including Next Generation Sequencing and advanced data analysis methods.
In summary we work for: A better understanding of how viral infections cause diseases. Preventing and treating viral infections more efficiently. Improved health in production animals for the benefit of both animal welfare and the economy of the farming industry.

Head of Section

Thomas N Kledal
Head of Life Science & Bioengineering Innovation
DTU Vet
+45 35 88 62 44