Enhancement of Muramyldipeptide (MDP) Immunostimulatory Activity by Controlled Multimerization on Dendrimers

Sørensen, Nanna Skall ; Boas, Ulrik ; Heegaard, Peter M. H.

in journal: Macromolecular Bioscience (ISSN: 1616-5187) (DOI: http://dx.doi.org/10.1002/mabi.201100105), vol: 11, issue: 11, pages: 1484-1490, 2011

Type: Journal article - Journal article

DOI: 10.1002/mabi.201100105

Dendrimers for Vaccine and Immunostimulatory Uses

Heegaard, Peter M. H. ; Boas, Ulrik ; Sørensen, Nanna Skall

in journal: Bioconjugate Chemistry (ISSN: 1043-1802) (DOI: http://dx.doi.org/10.1021/bc900290d), vol: 21, issue: 3, pages: 405-418, 2010

Type: Journal article - Journal article

DOI: 10.1021/bc900290d

Dendrimer based vaccine adjuvants

Heegaard, Peter M. H. ; Boas, Ulrik ; Sørensen, Nanna Skall

part of: Polymeric Micelles and Related Nano-delivery Systems, 2009, Kentus Book Publishers,

Type: Book chapter - Book chapter

A robust quantitative solid phase immunoassay for the acute phase protein C-reactive protein (CRP) based on cytidine 5 '-diphosphocholine coupled dendrimers

Heegaard, Peter M. H. ; Pedersen, H. G. ; Jensen, A. L. ; Boas, Ulrik

in journal: Journal of Immunological Methods (ISSN: 0022-1759) (DOI: http://dx.doi.org/10.1016/j.jim.2009.02.002), vol: 343, issue: 2, pages: 112-118, 2009

Type: Journal article - Journal article

DOI: 10.1016/j.jim.2009.02.002

IMMUNOSTIMULATORY PROPERTIES OF DENDRIMERS MULTIVALENTLY PRESENTING MURAMYLDIPEPTIDE

Sørensen, Nanna Skall ; Boas, Ulrik ; Heegaard, Peter M. H.

Type: Sound/Visual production (digital) - Sound/Visual production (digital)

Presented at: 2nd European Congress of Immunology, Berlin

Backbone Amide Linker in Solid-Phase Synthesis

Boas, Ulrik ; Brask, Jesper ; Jensen, K. J.

in journal: Chemical Reviews (ISSN: 0009-2665) (DOI: http://dx.doi.org/10.1021/cr068206r), vol: 109, issue: 5, pages: 2092-2118, 2009

Type: Journal article - Journal article

DOI: 10.1021/cr068206r

Towards molecular adjuvants and vaccines based on dendrimers

Boas, Ulrik

Type: Sound/Visual production (digital) - Sound/Visual production (digital)

Presented at: Organic Seminar Series 2008, KU-Farma

Dendrimers for multivalent display of immune modulating motifs

Boas, Ulrik

Type: Sound/Visual production (digital) - Sound/Visual production (digital)

Presented at: 1’st Bio-Dendrimer Symposium, Lodz, Poland

Dendrimers as scaffolds for immune stimulating motifs, a new approach to molecular adjuvants

Boas, Ulrik

Type: Sound/Visual production (digital) - Sound/Visual production (digital)

Presented at: Hyper-Nano workshop, Crete, Greece

Towards molecular adjuvants and vaccines based on dendrimers

Boas, Ulrik

Type: Conference abstract for conference - Conference abstract for conference

Presented at: Organic Seminar Series 2008, KU-Farma

THAL, a Sterically Unhindered Linker for the Solid-Phase Synthesis of acid sensitive protected peptide acids

Isidro-Llobet, A. ; Boas, Ulrik ; Jensen, K. J. ; Alvarez, M. ; Albericio, F.

in journal: The Journal of Organic Chemistry (ISSN: 0022-3263) (DOI: http://dx.doi.org/10.1021/jo800535m), vol: 73, pages: 7342-7344, 2008

Type: Journal article - Journal article

DOI: 10.1021/jo800535m

The dendrimer-PAMP concept as a novel type of adjuvant

Boas, Ulrik

Type: Sound/Visual production (digital) - Sound/Visual production (digital)

Presented at: Epizone workshop, DTU-Vet

Dendrimers destabilize proteins in a generation-dependent manner involving electrostatic interactions

Gichm, Lise ; Christensen, Casper ; Boas, Ulrik ; Heegaard, Peter M. H. ; Otzen, Daniel E.

in journal: Biopolymers (ISSN: 0006-3525) (DOI: http://dx.doi.org/10.1002/bip.20921), vol: 89, issue: 6, pages: 522-529, 2008

Type: Journal article - Journal article

DOI: 10.1002/bip.20921

A new efficient synthesis of isothiocyanates from amines using di-tert-butyl dicarbonate

Munch, Henrik ; Hansen, Jon S. ; Pittelkow, Michael ; Christensen, Jørn B. ; Boas, Ulrik

in journal: Tetrahedron Letters (ISSN: 0040-4039) (DOI: http://dx.doi.org/10.1016/j.tetlet.2008.03.045), vol: 49, issue: 19, pages: 3117-3119, 2008

Type: Journal article - Journal article

DOI: 10.1016/j.tetlet.2008.03.045

Molecular adjuvants using PAMP motifs: concept and methodology and effects on pig PBMCs

Sørensen, Nanna Skall ; Boas, Ulrik ; Heegaard, Peter M. H.

Type: Poster - Poster

Presented at: Biennial Meeting of the International Endotoxin and Innate Immunity Society, Edinbourgh, UK

S-((5-Formyl-3,4-ethylenedioxy)thiophene-2-yl)-3-propionic acid: Relationship between low formyl group reactivity and crystal structure

Hammershøj, P. ; Jessing, M. ; Madsen, A. Ø. ; Jensen, K. J. ; Christensen, J. B. ; Boas, Ulrik

in journal: International Journal of Peptide Research and Therapeutics (ISSN: 1573-3149), vol: 13, pages: 209-212, 2007

Type: Journal article - Journal article

Dendrimers as scaffolds for immune-stimulatory motifs

Sørensen, Nanna Skall ; Boas, Ulrik ; Skovgaard, Kerstin ; Jungersen, Gregers ; Heegaard, Peter M. H.

Type: Poster - Poster

Presented at: 8th International Veterinary Immunology Symposium, Ouro Preto

Dendrimers as scaffolds for immune-stimulatory motifs – a new class of well-defined molecular adjuvants

Sørensen, Nanna Skall ; Boas, Ulrik ; Skovgaard, Kerstin ; Jungersen, Gregers ; Heegaard, Peter M. H.

Type: Conference abstract for conference - Conference abstract for conference

Presented at: 8th International Veterinary Immunology Symposium, Ouro Preto

Dendrimers as scaffolds for immune-stimulatory motifs – a new class of well-defined molecular adjuvants

Sørensen, Nanna Skall ; Boas, Ulrik ; Skovgaard, Kerstin ; Jungersen, Gregers ; Heegaard, Peter M. H.

Type: Poster - Poster

Presented at: 8th International Veterinary Immunology Symposium, Ouro Preto

Dendrimers as scaffolds for molecular well defined adjuvants.

Boas, Ulrik ; Sørensen, Nanna Skall ; Heegaard, Peter M. H.

Type: Conference abstract for conference - Conference abstract for conference

Presented at: International Dendrimer Symposium, Toulouse, France