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Titel: Malignant lymphoma in a west Indian manatee (Trichechus manatus)
Type: Journal articleJournal article
Person(er):
Forfatter:  Hammer, Anne Sofie (Cwisno: 39025)
Technical University of Denmark

Forfatter:  Klausen, Bjarne
Technical University of Denmark

Forfatter:  Knold, Steffen
Technical University of Denmark

Forfatter:  Dietz, Hans H.
Technical University of Denmark

Forfatter:  Dutoit, Stephen J. Hamilton
Technical University of Denmark

Uddrag: We identified a malignant lymphoma infiltrating the lung, liver, kidney, mesenteric lymph nodes, and eye as the cause of death in a male West Indian manatee (Trichechus manatus). Diagnosis was based on gross histopathologic, and immunohistochemical studies. Tissue samples from ten organs were included in a tissue microarray and sections from this array were subjected to immunohistochemical staining. The cytoplasm of the neoplastic lymphocytes identified in six organs was positive for CD3, a marker for T-cell differentiation. The neoplastic cells were negative for CD79 alpha, a marker for B-cell differentiation. The cause of this neoplasm was not determined. This is the first report of malignant lymphoma in the mammal order Sirenia.
Publiceret: in journal: Journal of Wildlife Diseases (ISSN: 0090-3558), vol: 41, issue: 4, pages: 834-838, 2005
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