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| Title:
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Preliminary characterisation of Toxoplasma gondii isolates from Zimbabwe, with stage-specific monoclonal antibodies |
| Type:
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Journal articleJournal article |
| Participant(s):
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Forfatter:
Hove, T.
Technical University of Denmark
Technical University of Denmark
Email:
Forfatter:
Mukaratirwa, S.
Technical University of Denmark
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| Abstract:
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Cell-culture-derived clones of eight Toxoplasma gondii isolates from Zimbabwe were characterised in IFAT with a panel of five monoclonal antibodies (mAb). Each clone had been established from a single murine brain cyst. The antibodies were bradyzoite-specific (4.3), tachyzoite-specific (4.25, 5.1 and anti-P-30), or tachyzoite- and bradyzoite-specific (5.15). Their strong reactivity with the bradyzoite-specific mAb 4.3 and their weaker reactivity with the tachyzoite-specific 4.25, 5.1 and anti-P-30 indicated that all the isolates are probably of genetic type II. Each of the isolates reacted in the IFAT in a similar way to the Danish reference strain of T. gondii, SSI-119. |
| Published:
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in journal: Annals of Tropical Medicine and Parasitology (ISSN: 0003-4983) (DOI: http://dx.doi.org/10.1179/136485905X36280), vol: 99, issue: 4, pages: 377-382, 2005 |
| DOI:
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