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Title: COUPLING OF LIPOPOLYSACCHARIDE-DERIVED CARBOHYDRATES ONTO SOLID SURFACES
Type: PatentPatent
Participant(s):
Opfinder:  Jakobsen, M. H.
Technical University of Denmark

Inventor:  Boas, Ulrik (Cwisno: 39490)
Technical University of Denmark
Email:

Opfinder:  Jauho, E. S.
Technical University of Denmark

Inventor:  Heegaard, Peter M. H. (Cwisno: 39404)
Technical University of Denmark
Email:

Abstract: The present invention provides a method for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from KDO (2-keto-3-deoxy-D-mannooctonic acid), the method comprising the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM). Comprising a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria
Published:
See the publication in DTU Orbit See the publication in DTU Orbit

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